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Biomarkers and heart disease: What is translational success?

机译:生物标志物和心脏病:什么是转化成功?

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摘要

The term “biomarker” is a generic term that encompassesany measurable biological variable that is reflective of thepresence, progression, or therapeutic response to disease.Thus, biomarkers in cardiovascular disease could arguablyinclude clinical measurements such as heart rate, imagingmodalities such as cardiacMRI, or biochemical measurementsof fluid samples such as blood and urine. It is this lattercategory which has received considerable attention in termsof potential clinical application in the early screening, detection,risk stratification, diagnosis, and prognosis of heartdisease.
机译:术语“生物标志物”是一个通用术语,包括反映疾病存在、进展或治疗反应的任何可测量的生物变量。因此,心血管疾病中的生物标志物可以说包括心率等临床测量、心脏MRI等成像方式或血液和尿液等液体样本的生化测量。后一类在心脏病早期筛查、检测、风险分层、诊断和预后等方面的潜在临床应用受到了相当大的关注。

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