Most cited articles: ethanol-induced hepatotoxicity, anticarcinogenic effects of polyphenolic compounds in tea, dose-response modeling, novel roles of epoxide hydrolases and arsenic-induced suicidal erythrocyte death.

摘要

Every year, the editors of the Archives of Toxicology review the most cited articles from the previous 2 years (Table 1). This year, topping the most cited list (51 citations) is a comprehensive review by Arthur I. Cederbaum on the mechanisms of ethanol-induced liver injury, describing the contributions of oxidative stress and CYP2E1. The second most cited article also focuses on oxidative stress, but from a different perspective. Chung S. Yang describes how polyphenolic compounds in tea act as anticarcinogens.