Ultrasound detection of calcium pyrophosphate dihydrate crystal deposits in menisci: A pilot in vivo and ex vivo study

摘要

Over the last decade, ultrasonography (US) has been demonstrated to be an excellent technique for detecting calcium pyrophosphate dihydrate (CPP) crystal deposits in joints and periarticular tissues. The main difficulty in performing sensitivity and specificity studies for CPP crystal deposition disease is the definition of the gold standard for the diagnosis. The objective of our study was to define the sensitivity and specificity of US in detecting CPP crystal deposits in human menisci using polarised light microscopy as the gold standard.