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Metal-on-metal hips: Cobalt can induce an endotoxin-like response

机译:金属对金属臀部:钴可以诱导内毒素样反应

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Recent studies have highlighted significant risks associated with metal-on-metal (MoM) hip joint replacement,1 leading Smith a al2 to recommend that research should be 'focused on understanding the biological consequences of exposure to orthopaedic metals'. One of these consequences may be the development of solid or fluid-filled inflammatory lesions, termed pseudotumours, which have been reported in areas around MoM joints.The articulating surface of MoM joints is fabricated from a hard alloy containing approximately one part chromium to two of cobalt. Ionic forms of both these metals can be detected at a high level (<5 mM Cr,
机译:最近的研究强调了金属对金属(MoM)髋关节置换相关的重大风险,[1]导致Smith等[2]建议研究应“专注于了解骨科金属暴露的生物学后果”。这些后果之一可能是在MoM关节周围区域发生的称为假瘤的固体或液体填充炎症性病变的发展.MoM关节的关节表面是由一种硬质合金制成的,该合金含有大约一部分铬和其中一部分铬。钴。可以在MoM关节周围的滑液中以高水平(<5 mM Cr,

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