Synthesis and Structure of Quaternary Phosphonium Salts Based on Phosphorylated Sterically Hindered Phenols

摘要

A procedure was developed for the synthesis of quaternary phosphonium salts with two phosphorus atoms [P(III) and P(V)] based on phosphorylated hindered phenols. Stable phosphonium salts were obtained, the composition and structure of which were established by a complex of chemical, physical and physicochemical methods (~1H and ~(31)P NMR, IR spectroscopy, elemental and X-ray diffraction analysis). The resulting phosphonium salts have high antimicrobial activity against pathogenic and opportunistic microflora of humans and animals.