A Green Approach for the Synthesis of 1,4-Diphenylbutadiyne-1,3via C H Activated Aerobic C_(sp) C_(sp) Homocoupling Catalyzed by CuFe2O4 Nanoparticles.

摘要

An inexpensive, simple, and greener catalytic system with lower toxicity using CuFe2O4 nanoparticles in the presence of piperidine and dry toluene as a solvent has been reported for the synthesis of 1,4-diphenylbutadiyne-1,3, via CH activated aerobic C_(sp)C_(sp) homocoupling. This protocol provides 66 of yield at the gram-scale level making it appropriate for production at a larger scale. The catalyst shows reusability for up to five cycles without losing any significant catalytic activity.