A review on fabrication,actuation,and application of magnetic force driven,light driven and DNA nano/microrobots in modern theranostics

摘要

Consistent progress in therapeutics is important to overcome the emerging challenges in human health and diseases.Nano/microrobots are one of the most advanced types of nano/microscale particles with self-propagating ability,and have significantly addressed human health related challenges.These nano/microrobots are the combinational outcomes of technology with nanoscience,and piqued the interest of many researchers worldwide.The most notable achievement in this field is active targeting and on-demand controlled motion of nano/microrobots,reducing the driving time in the circulatory system and off-target accumulation,which is difficult to achieve in traditional drug delivery systems.Our discussion in the review includes fabrication processes,actuation mechanisms of DNA,magnetic force driven and light driven nano/microrobots,and their applications in various disease theranostics.Finally,we concluded with the advantages of nano/microrobots over conventional nano/microparticles and their limitations and future prospects.