Multiple pretibial cutaneous relapses of acute myeloblastic leukemia after allogeneic BMT.

摘要

Leukemia cutis is the infiltration of the skin by malignant hematopoietic cells. Any type of leukemia can disseminate to the skin, but this occurs most frequently in myeloid leukemias with monocytic differentiation, which presents with specific cutaneous involvement in ~ 25-31% of cases, and less frequently in AML, in 10% of cases.~1-3 It is widely recognized that the onset of cutaneous involvement in leukemia as a specific skin infiltration carries a poor prognosis.~4 We report the case of a woman diagnosed with AML who underwent allogeneic BMT and who presented with six consecutive cutaneous relapses, always confined to the same area and in the absence of peripheral blood or BM involvement.