Ovarian shielding allows ovarian recovery and normal birth in female hematopoietic SCT recipients undergoing TBI

摘要

Ovarian shielding successfully preserved ovarian function in the majority of patients who underwent TBI without any apparent increased risk of relapse after transplantation. However, it may be prudent to excludepatients with active leukemia due to the decreased irradiation dose delivered to the ovaries and pelvis. Physicians should seek to preserve fertility in young female patients undergoing hematopoietic SCT by means of both ovarian shielding and the preservation of embryos or oocytes.