LETTER TO THE EDITOR Human parvovirus B19 infection with GvHD-like erythema in two allogeneic stem cell transplant recipients

摘要

We report two cases of human parvovirus B19 infection as a rare but anticipated complication shortly after allogeneic peripheral blood stem cell transplantation (PBSCT), which were self-limiting in their course. The first patient was a 48-year-old female treated for secondary acute myeloid leukaemia (AML) FAB M2 following chemotherapy for breast cancer 7 years ago. She received a PBSCT in second complete remission, from a matched unrelated donor, after conditioning with 2Gy total-body irradiation, 120mg/m~2 fludarabine, 60mg/kg cyclophosphamide and 30mg/kg antithymocyte globulin. Immunosuppressive therapy was initiated with cyclospor-ine and mycofenolate.