首页> 外文期刊>Annals of surgical oncology >Angiogenesis-Related Markers and Prognosis After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy for Metastatic Colorectal Cancer
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Angiogenesis-Related Markers and Prognosis After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy for Metastatic Colorectal Cancer

机译:转移性结直肠癌的细胞减少手术和高温腹膜内化学疗法后血管生成相关的标志物和预后

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摘要

Patients presenting with peritoneal metastases (PM) of colorectal cancer (CRC) can be curatively treated with cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC). Angiogenesis is under control of multiple molecules of which HIF1a, SDF1, CXCR4, and VEGF are key players. We investigated these angiogenesis-related markers and their prognostic value in patients with PM arising from CRC treated with CRS and HIPEC.
机译:患有大肠癌(CRC)腹膜转移(PM)的患者可以通过细胞减灭术(CRS)和高温腹膜内化疗(HIPEC)进行治愈。血管生成受到多个分子的控制,其中HIF1a,SDF1,CXCR4和VEGF是关键分子。我们研究了这些血管生成相关的标志物及其在由CRS和HIPEC治疗的CRC引起的PM患者中的预后价值。

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