首页> 外文期刊>Archives Italiennes de Biologie >IMPAIRED AGONISTS RECRUITMENT DURING VOLUNTARY ARM MOVEMENTS IN PATIENTS AFFECTED BY SPASMODIC TORTICOLLIS
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IMPAIRED AGONISTS RECRUITMENT DURING VOLUNTARY ARM MOVEMENTS IN PATIENTS AFFECTED BY SPASMODIC TORTICOLLIS

机译:散发性TolitCOLLIS病人中自愿性手臂运动过程中受损的激动剂补充

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摘要

It is known that dystonia is a chronic movement disorder characterised by sustained muscle contraction which causes an abnormal posture. Dystonia may affect a single part of the body (focal dystonia), two or more adjacent areas (segmental dystonia) or be generalised throughout the body (idiopatic torsion dystonia). In addition to the disorders of postural tone, the body segments affected by these pathologies show also disorders of voluntary movements. In particular, Van der Kamp (21), in a study performed on a group of patients with upper limb dystonia, showed that rapid, self-paced and self-determined, single joint movements (elbow flexion) were slower and more variable in amplitude in these patients than in normal subjects. Normally such movements are performed by an initial burst of agonist muscles (AG1), followed by a recruitment of the antagonists (ANT) and, finally, by a second agonist activation (AG2), which brings the joint to its final position. Alterations in the triphasic EMG pattern, such as a longer duration of AG1, co-contraction of agonist and antagonist muscles, and spread of activation to muscles not normally involved in the movement, could be observed in patients.
机译:众所周知,肌张力障碍是一种慢性运动障碍,其特征在于持续的肌肉收缩会导致姿势异常。肌张力障碍可影响身体的单个部位(局灶性肌张力障碍),两个或多个相邻区域(节段性肌张力障碍)或在全身广泛传播(绝经性扭转肌张力障碍)。除了姿势音调障碍外,受这些病理影响的身体部位也显示出自发性运动障碍。特别是,Van der Kamp(21)在对一组上肢肌张力障碍患者进行的研究中显示,快速,自定进度和自定的单关节运动(肘关节屈曲)速度较慢且幅度变化较大这些病人比正常人要多。通常,这样的运动是通过最初的激动剂肌肉爆发(AG1),然后招募拮抗剂(ANT),最后通过第二次激动剂激活(AG2)将关节恢复到最终位置来进行的。在患者中可以观察到三相肌电图模式的改变,例如更长的AG1持续时间,激动剂和拮抗肌的共同收缩以及激活扩散到通常不参与运动的肌肉中。

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