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Beware the software

机译:当心软件

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摘要

Over the last several months, many of the readers have been introduced to details of the Vioxx (rofecoxib; Merck & Co., Whitehouse Station, NJ) case through the mass media and the scientific literature. Facts about the pharmaceutical company's knowledge of the deaths that were directly linked to Vioxx use have come to light. In addition, there have been several reports of industry efforts to counter or cover its negative effects.One of the discoveries is directly relevant to the issue of scientific misconduct in publication. One of the original articles that reported on the Vioxx Gastrointestinal Outcomes Research study was published in the New England Journal of Medicine (NEJM), including reports of fewer incidences of stomach ulcers and bleeding with Vioxx compared to those with other medications (Bombardier et al., 2000). Other scientists-essentially calling into question
机译:在过去的几个月中,通过大众媒体和科学文献向许多读者介绍了Vioxx(罗非考昔;默克公司,新泽西州怀特豪斯站)的详细情况。有关该制药公司对与使用Vioxx直接相关的死亡的认识的事实已经暴露出来。此外,还有几篇有关行业为抵制或掩盖其负面影响而做出的努力的报告。其中一项发现与出版物中的科学不当行为直接相关。在新英格兰医学杂志(NEJM)上发表了有关Vioxx胃肠道结局研究的报道的原始文章之一,其中包括与其他药物相比,Vioxx发生胃溃疡和出血的发生率更低的报道(Bombardier等。 ,2000)。其他科学家-基本上引起了质疑

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