Household based treatment of drinking water with flocculant-disinfectant for preventing diarrhoea in areas with turbid source water in rural western Kenya: cluster randomised controlled trial

摘要

Objective To compare the effect on prevalence of diarrhoea and mortality of household based treatment of drinking water with flocculant-disinfectant, sodium hypochlorite, and standard practices in areas with turbid water source in Africa. Design Cluster randomised controlled trial over 20 weeks.Setting Family compounds, each containing several houses, in rural western Kenya. Participants 6650 people in 605 family compounds. Intervention Water treatment: flocculant-disinfectant, sodium hypochlorite, and usual practice (control). Main outcome measures Prevalence of diarrhoea and all cause mortality. Escherichia coli concentration, free residual chlorine concentration, and turbidity in household drinking water as surrogates for effectiveness of water treatment.