Should nifedipine be used to counter low blood sugar levels in children with persistent hyperinsulinaemic hypoglycaemia?

摘要

A 5 year old boy, suffering from hyperinsulinaemic hypoglycaemia since infancy and arterial hypertension secondary to polycystic kidney disease, was given nifedipine (0.3 mg/kg three times a day) to treat his high blood pressure. Normotension was restored and his blood sugar levels normalised. We wondered whether nifedipine could be used safely as long term treatment to counter hypoglycaemia in persistent hyperinsulinaemic hypoglycaemia of infancy (PHHI)?