Response to high-dose dexamethasone for acquired pure red cell aplasia following ABO-mismatched allogeneic stem cell transplantation.

摘要

We report a case of pure red cell aplasia (PRCA) following allogeneic peripheral blood stem cell transplantation (PBSCT) for aplastic anemia with major ABO mismatch that proved resistant to all standard treatment options including oral prednisolone, reduction in immunosuppres-sive treatment, erythropoietin (EPO) and Rituximab. Finally, high-dose dexamethasone for 4 days resolved the PRCA in our patient, 388 days after SCT and 40 days after the first dose of dexamethasone.