Maternal allopurinol administration during suspected fetal hypoxia: a novel neuroprotective intervention? A multicentre randomised placebo controlled trial

Kaandorp Joepe J.; Benders Manon J. N. L.; Schuit Ewoud; Rademaker Carin M. A.; Oudijk Martijn A.; Porath Martina M.; Oetomo Sidarto Bambang; Wouters Maurice G. A. J.; van Elburg Ruurd M.; Franssen Maureen T. M.; Bos Arie F.; de Haan Timo R.; Boon Janine; de Boer Inge P.; Rijnders Robbert J. P.; Jacobs Corrie J. W. F. M.; Scheepers Liesbeth H. C. J.; Gavilanes Danilo A. W.; Bloemenkamp Kitty W. M.; Rijken Monique; van Meir Claudia A.; von Lindern Jeannette S.; Huisjes Anjoke J. M.; Bakker Saskia C. M. J. E. R.; Mo Ben W. J.; Visser Gerard H. A.; Van Bel Frank; Derks Jan B.

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Maternal allopurinol administration during suspected fetal hypoxia: a novel neuroprotective intervention? A multicentre randomised placebo controlled trial

机译：在怀疑胎儿缺氧期间给予母源别嘌呤醇：一种新型的神经保护性干预措施？多中心随机安慰剂对照试验

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Objective To determine whether maternal allopurinol treatment during suspected fetal hypoxia would reduce the release of biomarkers associated with neonatal brain damage.

机译：目的确定在怀疑胎儿缺氧期间母亲别嘌醇治疗是否会减少与新生儿脑损伤相关的生物标志物的释放。

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《Archives of disease in childhood. Fetal and neonatal edition》 |2015年第3期|共8页
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Kaandorp Joepe J.; Benders Manon J. N. L.; Schuit Ewoud; Rademaker Carin M. A.; Oudijk Martijn A.; Porath Martina M.; Oetomo Sidarto Bambang; Wouters Maurice G. A. J.; van Elburg Ruurd M.; Franssen Maureen T. M.; Bos Arie F.; de Haan Timo R.; Boon Janine; de Boer Inge P.; Rijnders Robbert J. P.; Jacobs Corrie J. W. F. M.; Scheepers Liesbeth H. C. J.; Gavilanes Danilo A. W.; Bloemenkamp Kitty W. M.; Rijken Monique; van Meir Claudia A.; von Lindern Jeannette S.; Huisjes Anjoke J. M.; Bakker Saskia C. M. J. E. R.; Mo Ben W. J.; Visser Gerard H. A.; Van Bel Frank; Derks Jan B.;
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1. Maternal allopurinol administration during suspected fetal hypoxia: a novel neuroprotective intervention? A multicentre randomised placebo controlled trial [J] . Kaandorp Joepe J., Benders Manon J. N. L., Schuit Ewoud, Archives of disease in childhood. Fetal and neonatal edition . 2015,第3期

机译：在怀疑胎儿缺氧期间给予母源别嘌呤醇：一种新型的神经保护性干预措施？多中心随机安慰剂对照试验
2. Protect-me: a parallel-group, triple blinded, placebo-controlled randomised clinical trial protocol assessing antenatal maternal melatonin supplementation for fetal neuroprotection in early-onset fetal growth restriction [J] . Kirsten R Palmer, Joanne C Mockler, Miranda L Davies-Tuck, BMJ Open . 2019,第6期

机译：Protect-me：一项平行组，三盲，安慰剂对照的随机临床试验方案，评估产前母体褪黑激素补充对早发胎儿生长限制的胎儿神经保护作用
3. The NIFTY study: A multicentre randomised double-blind placebo-controlled trial of nifedipine maintenance tocolysis in fetal fibronectin-positive women in threatened preterm labour [J] . ParryE., RoosC., StoneP., Australian and New Zealand Journal of Obstetrics and Gynecology . 2014,第3期

机译：NIFTY研究：早产先兆的胎儿纤连蛋白阳性女性中硝苯地平维持生育的多中心随机双盲安慰剂对照试验
4. Intrahepatic Cholestasis of Pregnancy: A Placebo-controlled Randomized Trial of Ursodeoxycholic Acid Vs. Dexamethasone On Maternal and Fetal Outcome and Metabolism [C] . A. Glantz, H.-u. Marschall, F. Lammert, Falk Symposium . 2003

机译：妊娠的肝内胆汁淤积：一种安慰剂对照的核糖核酸随机试验与母亲和胎儿结果和新陈代谢的地塞米松
5. Sexuality and gynaecological cancer: A randomised control trial to evaluate the effectiveness of a group psychoeducational intervention in improving the sexual health of women with gynaecological cancer treated with radiotherapy [D] . Jeffries, Sherryl Anne 2003

机译：性与妇科癌症：一项随机对照试验，旨在评估团体心理教育干预措施对经放射治疗的妇科癌症妇女改善性健康的有效性
6. Behavioral and neurodevelopmental outcome of children after maternal allopurinol administration during suspected fetal hypoxia: 5-year follow up of the ALLO-trial [O] . Job Klumper, Joepe J. Kaandorp, Ewoud Schuit, 2012

机译：孕妇在怀疑胎儿缺氧期间服用别嘌醇后的行为和神经发育结局：ALLO试验的5年随访
7. 170 Maternal Allopurinol Administration During Term Labor is Neuroprotective in Case of Fetal Hypoxia; A Multicenter Randomized Placebo Controlled Trial [O] . J. Kaandorp, M. Benders, E. Schuit, 2012

机译：170母乳血尿疗法在胎儿缺氧的情况下是神经保护;多中心随机安慰剂对照试验

Maternal allopurinol administration during suspected fetal hypoxia: a novel neuroprotective intervention? A multicentre randomised placebo controlled trial

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