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Cerebral palsy and socioeconomic status: a retrospective cohort study.

机译:脑瘫与社会经济地位:一项回顾性队列研究。

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AIMS: To study the relation between risk of cerebral palsy and socioeconomic status. METHODS: A total of 293 children with a diagnosis of cerebral palsy out of 105,760 live births between 1 January 1982 and 31 December 1997 were identified from the special conditions sub-file of the West Sussex Computerised Child Health System. RESULTS: There was a linear association between risk of cerebral palsy and socioeconomic status (SES) measured by the Registrar General's social class (RGSC) and enumeration district (ED) ranked into quintiles by the Townsend Deprivation Index derived from 1991 census data. Fifty one per cent and 30% of cases of cerebral palsy were statistically "attributable" to inequality in SES using the RGSC and ED quintile respectively. A linear association was also noted for singleton live births. The association between risk of cerebral palsy and ED quintile persisted in a logistic regression model that included birth weight and gestational age, although that between RGSC and cerebral palsy no longer reached conventional levels of statistical significance after adjustment. CONCLUSIONS: A strong association was observed between socioeconomic status and the risk of cerebral palsy, which was only partly accounted for by the known social gradients in birth weight and gestational age.
机译:目的:研究脑瘫风险与社会经济地位之间的关系。方法:从西萨塞克斯郡儿童计算机医疗系统的特殊条件子档案中,识别出1982年1月1日至1997年12月31日期间105,760例活产中的293名诊断为脑瘫的儿童。结果:根据1991年人口普查数据得出的Townsend贫困指数,总书记官长的社会阶层(RGSC)和枚举区(ED)将脑瘫风险与社会经济地位(SES)进行了线性关联。统计上分别使用RGSC和ED五分位数,分别有51%和30%的脑瘫病例归因于SES不平等。单胎活产也发现线性关联。在包括出生体重和胎龄的逻辑回归模型中,脑瘫和ED五分位数风险之间的关联仍然存在,尽管调整后RGSC和脑瘫之间的关联不再达到常规的统计显着性水平。结论:社会经济状况与脑瘫风险之间存在密切的关联,这仅部分是由于出生体重和胎龄的已知社会梯度造成的。

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