In this issue

摘要

Our colorful cover features a H&E staining of brain sections from one glioma-bearing mouse upon chronic administration of antibiotics. Antibiotic treatment affects gut microbiota, potentiates glioma growth and impairs innate tumor immune surveillance. The image is taken from D'Alessandro et al. (pp. 705-711), where the authors present data supporting a functional gut-immune-brain axis in a murine glioma model, and propose to modulate this communication pathway to counteract brain tumor immunosuppression. The color of the image has been digitally altered for the cover.