'Guessing it right,' John A. Simpson, and myasthenia gravis: the role of analogy in science.

摘要

In 1960, John A. Simpson hypothesized that myasthenia gravis "is an 'auto-immune' response of muscle in which an antibody to end-plate protein may be formed." Simpson's speculation was subsequently shown to be correct. A review of Simpson's hypothesis from a historical perspective illustrates the role of analogy in science.