Towards evidence based medicine for paediatricians-QUESTION 2: Does topical local anaesthetic reduce pain from vaccinations in infants?

摘要

SCENARIO: You are about to give a 2-month-old baby her first vaccinations. You wonder if there is a role for topical local anaesthetics in reducing pain from intramuscular injection of vaccinations. STRUCTURED CLINICAL QUESTION: In an infant undergoing intramuscular vaccination injection (patient) does topical local anaesthetic (intervention) compared with placebo (control) reduce pain (outcome).