Reflecting on the relationship between aggressiveness of tumor pathology and epilepsy, as many as 80% of patients with low-grade tumors present with seizures. The frontal lobe, temporal lobe, and insular regions are the most common sites of tumors that produce seizures. In contrast, 42% of patients with glioblastoma multiforme, have seizures as the presenting symptom; ultimately, 62% of these patients will develop some form of seizures.
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