Non-EEG seizure detection is here

摘要

A patient has generalized tonic-clonic seizures (GTCS) despite taking 3 antiepileptic drugs and dies suddenly in the shower. A similar patient falls asleep while watching television on the couchhis wife finds him face down, dead, in the morning. These catastrophic outcomes are due to sudden unexpected death in epilepsy (SUDEP) and may be preventable.(1,2) Following GTCS, most patients develop postictal EEG suppression with immobility and respiratory dysfunction.(3-5) A prone sleeping position appears to increase risks that a patient will asphyxiate following convulsive seizures and develop terminal apnea and arrhythmias. A separate group of patients with focal seizures appear to develop autonomic dysfunction and lethal arrhythmias.(6) So how might we reduce risks for SUDEP?