Diagnostic property of cervical phosphorylated insulin-like growth factor binding protein-1 in the prediction of preterm labor in symptomatic patients

摘要

Insulin-like growth factor binding protein-1 is a specific protein that is proposed for its clinical significance role as a predictor for preterm labor in symptomatic patients. Altinkaya et al. recently published their interesting observation in Arch Gynecol Obstet that detection of this specific protein by was a rapid and easily applicable test that highly predicted preterm delivery [1]. However, the diagnostic property of the test for this protein is still a questionable concern in laboratory medicine. The wide range of sensitivity and specificity of the diagnostic property of cervical phosphorylated insulin-like growth factor binding protein-1 in the prediction of preterm labor in symptomatic patients can be seen in the publications from different settings (Table 1).