• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Archives of Gerontology and Geriatrics: An International Journal Integrating Experimental, Clinical and Social Studies on Ageing >Difference in average survival between F344/Du and F344/N rats is not due to genetic contamination.
【24h】

Difference in average survival between F344/Du and F344/N rats is not due to genetic contamination.

机译：F344 / Du和F344 / N大鼠之间的平均存活率差异不是由于基因污染。

获取原文
获取原文并翻译 | 示例
       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The average survival was found to be different between substrains of rats, F344/Du and F344/N. One of the causes of this difference could have been genetic contamination by crossbreeding with other strain(s) after the divergence of substrains. These two strains were examined by PCR-SSLP (simple sequence length polymorphism) procedure using microsatellite (Mit) markers to identify the contamination. All 288 Mit markers distributed throughout the genome exhibited no size polymorphisms between these two strains. This indicated that there was no genetic contamination between these two strains. The phenotypic difference in average survival, thus, is not due to genetic contamination.
机译：发现大鼠的亚株F344 / Du和F344 / N之间的平均存活率是不同的。造成这种差异的原因之一可能是在亚菌株发散后，通过与其他菌株进行杂交而造成的遗传污染。通过PCR-SSLP（简单序列长度多态性）程序使用微卫星（Mit）标记对这两个菌株进行了检测，以鉴定污染。分布在整个基因组中的所有288个Mit标记在这两个菌株之间均未显示大小多态性。这表明这两个菌株之间没有遗传污染。因此，平均存活率的表型差异不是由于遗传污染。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号