Synthesis and biological evaluation of novel (thio)urea derivatives as potential antitumor agents.

Jin C; Liang YJ; He H; Fu L

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Synthesis and biological evaluation of novel (thio)urea derivatives as potential antitumor agents.

机译：新型（硫）脲衍生物作为潜在抗肿瘤药的合成及生物学评价。

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A series of novel (thio)ureas containing the pyrimidinyl group was designed and synthesized. Their in-vitro antitumor activity against different human tumor cells was examined. Some of the compounds showed potential antitumor activity, which provided some hints for further studies on structure modification.

机译：设计并合成了一系列含有嘧啶基的新型（硫）脲。检查了它们对不同人类肿瘤细胞的体外抗肿瘤活性。一些化合物显示出潜在的抗肿瘤活性，这为进一步研究结构修饰提供了一些提示。

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《Archiv der Pharmazie》 |2011年第11期|共4页
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Jin C; Liang YJ; He H; Fu L;
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中图分类药学;
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Synthesis and biological evaluation of novel (thio)urea derivatives as potential antitumor agents.

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