Synthesis, Spectroscopic Characterization, Antimicrobial Pesticidal and Nematicidal Activity of Some Nitrogen-Oxygen and Nitrogen-Sulfur donor Coumarins based Ligands and their Organotin(IV) Complexes

摘要

Series of new tin complexes are synthesized by classical thermal and microwave-irradiated techniques. The biologically potent ligands 3-formyl-4-chlorocoumarin semicarbazone (L~1H) and 3-formyl-4-chlorocoumarin thiosemicarbazone (L~2H), were prepared by the condensation of semicarbazide hydrochloride and thiosemicarbazide in ethanol with the particular ketone by using microwave as well as conventional methods. The tin(IV) complexes have been prepared by mixing Ph3SnCl/Me3SriCI/IMe2SnCl2 in 1:1 and 1:2 molar ratios with monofunctional bidentate ligands. The structures of the ligands and their tin complexes were confirmed by the elemental analysis, melting point determinations, molecular weight determinations, IR,~1H NMR, ~(13)C NMR, ~(119)Sn NMR, UV, mass spectral and X-ray powder diffraction studies. On the basis of these studies it is clear that the ligands coordinated to the metal atom in a monobasic bidentate mode, by X~n N donor system. Thus, suitable trigonal bipyramidal geometry for penta-coordinated state and octahedral geometry for hexa-coordinated state have been suggested for the 1:1 and 1:2 metal compounds. Both the ligands and their complexes have been screened for their antimicrobial, pesticidal and nematicidal activities.