An efficient Stifle cross-coupling reaction catalyzed by ortho-palladated complex of tribenzylamine under microwave irradiation

摘要

The catalytic activity of [Pd{C6H4(CH2N(CH2ph)2)}(μ-Br)]2 complex as an efficient, stable and catalyst that is non-sensitive to air and moisture was investigated in the Stille cross-coupling reaction of various aryl halides with phenyltributyltins under microwave irradiation. The substituted biaryls were produced in excellent yield in short reaction times using a catalytic amount of this complex in DMF at 100C. The combination of dimeric complex as homogeneous catalyst and microwave irradiation and also DMF as microwave-active polar solvent gave higher yields in shorter reaction times.