Lewis Acid-Catalyzed Electrophilic Trifluoromethylthiolation of (Hetero)Arenes

摘要

(N-Trifluoromethylthio) saccharin has been applied as an electrophilic trifluoromethylthiolating reagent for a broad scope of heteroarenes, electron-donating group (EDG)-activated benzenes, and several electron-rich olefins. Iron(III) and gold(III) catalysts showed complementary activity for different substrates.