Catalytic Carbon-Fluorine Bond Activation with Monocoordinated Nickel-Carbene Complexes: Reduction of Fluoroarenes

摘要

Monocoordinate nickel/N-heterocyclic carbene complexes reveal unexpected reactivity towards aryl fluorides. Defluorination reactions were efficiently performed with a beta-hydrogen-containing alkoxide (3 equiv.) in the presence of 3 mol% of [1:1] Ni(0)/IMes·HCl catalyst (IMes = 1,3-dimesitylimidazol-2-ylidene).