Regioselective Addition Reactions of Propargyl Bromides to Carbonyl Compounds with Gallium Catalyzed by Indium

摘要

Reactions of organogallium reagents generated from propargyl bromides having substituents at the y-position and gallium in the presence of 5 mol % of indium with aldehydes and ketones selectively produced homoallenyl alcohols in good to excellent yields.Treatment of organogallium reagents obtained from propargyl bromide or propargyl bromides having substituents at the alpha-position and gallium in the presence of 5 mol % of indium with car-bonyl compounds selectively afforded homoproparg-yl alcohols.