AmpC {beta}-Lactamase in an Escherichia coli Clinical Isolate Confers Resistance to Expanded-Spectrum Cephalosporins.

Nordmann P

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AmpC {beta}-Lactamase in an Escherichia coli Clinical Isolate Confers Resistance to Expanded-Spectrum Cephalosporins.

机译：大肠杆菌临床分离株中的AmpCβ-内酰胺酶赋予对扩谱头孢菌素的抗性。

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Cloning, sequencing, and biochemical analysis identified a novel AmpC-type beta-lactamase conferring resistance to extended-spectrum cephalosporins in an Escherichia coli clinical isolate. This enzyme, exhibiting 14 amino acid substitutions compared to a reference AmpC cephalosporinase of E. coli, hydrolyzed ceftazidime and cefepime significantly.

机译：克隆，测序和生化分析确定了一种新型AmpC型β-内酰胺酶，可赋予大肠埃希菌临床分离株对广谱头孢菌素的抗性。与大肠杆菌的参考AmpC头孢菌素酶相比，该酶具有14个氨基酸取代，水解头孢他啶和头孢吡肟明显。

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《Antimicrobial agents and chemotherapy.》 |2004年第10期|共4页
作者
Nordmann P;
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正文语种 eng
中图分类药学;
关键词
Escherichia coli; Clinical; Cephalosporins; social resistance; Lactamase; 大肠杆菌; 头孢菌素类;

机译：Escherichia coli;Clinical;Cephalosporins;social resistance;Lactamase;大肠杆菌;头孢菌素类;

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1. AmpC {beta}-Lactamase in an Escherichia coli Clinical Isolate Confers Resistance to Expanded-Spectrum Cephalosporins. [J] . Nordmann P Antimicrobial agents and chemotherapy. . 2004,第10期

机译：大肠杆菌临床分离株中的AmpCβ-内酰胺酶赋予对扩谱头孢菌素的抗性。
2. The association between extended spectrum beta-lactamase (ESBL) and ampicillin C (AmpC) beta-lactamase genes with multidrug resistance in Escherichia coli isolates recovered from turkeys in Brazil [J] . Hoepers P. G., Silva P. L., Rossi D. A., British Poultry Science . 2018,第4期

机译：扩展光谱β-内酰胺酶（ESBL）和氨苄青霉素C（AMPC）β-内酰胺酶基因与大肠杆菌中的多药耐药性的β-内酰胺酶基因在巴西的火鸡中回收中
3. Determination of extended spectrum beta-lactamases/AmpC beta-lactamases and plasmid-mediated quinolone resistance in Escherichia coli isolates obtained from bovine carcasses in Mexico [J] . Aguilar-Montes de Oca Saul, Talavera-Rojas Martin, Soriano-Vargas Edgardo, Tropical Animal Health and Production . 2015,第5期

机译：从墨西哥牛car体获得的大肠杆菌分离株中超广谱β-内酰胺酶/ AmpCβ-内酰胺酶和质粒介导的喹诺酮抗性的测定
4. Study of Drug Resistance in Clinical Isolates of Enterococci with special reference to high level aminoglycoside resistance, beta lactamase production and lateral transfer of drug resistance [C] . M.G. Karmarkar, Edwin S. Gershom, Santosh Kaul, Lancefield International Symposium on Streptococci and Streptococcal Diseases . 2006

机译：肠球菌临床分离株的耐药性研究，特别是高水平氨基糖苷抵抗，β内酰胺酶生产和耐药性横向转移
5. Prevalence of Extended-Spectrum β-Lactamase-Producing Enterobacteriaceae with Focus on the Molecular Characterization of ESBL- and AmpC β-Lactamase-Producing Escherichia coli Isolated in Canadian Hospitals from 2005-2009 [D] . Simner, Patricia Jeanne 2011

机译：2005-2009年在加拿大医院分离的产广谱β-内酰胺酶肠杆菌的流行情况，侧重于生产ESBL和AmpCβ-内酰胺酶的大肠杆菌的分子表征
6. AmpC β-Lactamase in an Escherichia coli Clinical Isolate Confers Resistance to Expanded-Spectrum Cephalosporins [O] . Hedi Mammeri, Hasan Nazic, Thierry Naas, 2004

机译：大肠杆菌临床分离株中的AmpCβ-内酰胺酶赋予对扩频头孢菌素的抗药性
7. AmpC β-Lactamase in an Escherichia coli Clinical Isolate Confers Resistance to Expanded-Spectrum Cephalosporins [O] . Mammeri, Hedi, Nazic, Hasan, Naas, Thierry, 2004

机译：大肠杆菌临床分离株中的AmpCβ-内酰胺酶赋予对扩频头孢菌素的抗药性

AmpC {beta}-Lactamase in an Escherichia coli Clinical Isolate Confers Resistance to Expanded-Spectrum Cephalosporins.

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