Coding and noncoding: the CLL mix.

摘要

In this issue of Blood, Palamarchuk and colleagues present interesting evidence that deletions in chromosome 13q result in a loss of expression of both the protein coding gene, dleu7 as well as the noncoding RNA cluster miR-15a-16-1. dleu7 and miR15a-16-1 may both have a role in the pathogenesis of CLL.