Treatment of Staphylococcus aureus biofilm infection by the quorum-sensing inhibitor RIP.

Balaban N; Cirioni O; Giacometti A; Ghiselli R; Braunstein JB; Silvestri C; Mocchegiani F; Saba V; Scalise G

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Treatment of Staphylococcus aureus biofilm infection by the quorum-sensing inhibitor RIP.

机译：群体感应抑制剂RIP治疗金黄色葡萄球菌生物膜感染。

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The quorum-sensing inhibitor RIP inhibits staphylococcal TRAP/agr systems and both TRAP- and agr-negative strains are deficient in biofilm formation in vivo, indicating the importance of quorum sensing to biofilms in the host. RIP injected systemically into rats has been found to have strong activity in preventing methicillin-resistant Staphylococcus aureus graft infections, suggesting that RIP can be used as a therapeutic agent.

机译：群体感应抑制剂RIP抑制葡萄球菌TRAP / agr系统，TRAP和agr阴性菌株在体内生物膜形成方面均不足，表明群体感应对宿主生物膜的重要性。已发现将RIP全身注射入大鼠具有预防耐甲氧西林的金黄色葡萄球菌移植物感染的强大活性，这表明RIP可用作治疗剂。

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来源
《Antimicrobial agents and chemotherapy.》 |2007年第6期|共4页
作者
Balaban N; Cirioni O; Giacometti A; Ghiselli R; Braunstein JB; Silvestri C; Mocchegiani F; Saba V; Scalise G;
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原文格式 PDF
正文语种 eng
中图分类治疗学;
关键词
biomolecular film; Staphylococcus aureus; Infection as complication of medical care; 葡萄球菌; 金黄色;

机译：biomolecular film;Staphylococcus aureus;Infection as complication of medical care;葡萄球菌;金黄色;

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1. Treatment of Staphylococcus aureus biofilm infection by the quorum-sensing inhibitor RIP. [J] . Balaban N, Cirioni O, Giacometti A, Antimicrobial agents and chemotherapy. . 2007,第6期

机译：群体感应抑制剂RIP治疗金黄色葡萄球菌生物膜感染。
2. A Microporous Zn(Ⅱ)-MOF for Solvent-Free Cyanosilylation and Treatment Effect Against Bacterial Infection on Burn Patients Via Inhibiting the Staphylococcus aureus Biofilm Formation [J] . Chen Xiao-Yan, Ji Peng Journal of inorganic and organometallic polymers and materials . 2021,第2期

机译：一种微孔Zn（Ⅱ）-mmof用于无溶剂氰基甲硅烷化和治疗效果免受抑制烧伤患者的细菌感染葡萄球菌生物膜形成
3. Development of a biofilm inhibitor molecule against multidrug resistant Staphylococcus aureus associated with gestational urinary tract infections [J] . P. Balamurugan, M. Hema, Gurmeet Kaur, Frontiers in Microbiology . 2015,第6期

机译：抵抗与妊娠尿路感染相关的多药耐药性金黄色葡萄球菌的生物膜抑制剂分子的开发
4. Impact of step size on histotripsy treatment of staphylococcus aureus biofilms on surgical mesh [C] . Timothy A. Bigelow, Clayton Thomas, Huaiqing Wu, IEEE International Ultrasonics Symposium . 2017

机译：步幅对手术网片金黄色葡萄球菌生物膜组织治疗的影响
5. Enzymatic Depletion of Pyruvate using Pyruvate Dehydrogenase Induces Dispersion of Pseudomonas aeruginosa and Staphylococcus aureus Biofilms and Poses a Potentially Powerful Anti-Biofilm Treatment Strategy for Chronic Burn Wound Infections [D] . Goodwine, James Stephen. 2018

机译：使用丙酮酸脱氢酶诱导丙酮酸丙酮酸的酶促耗尽铜绿假单胞菌和金黄色葡萄球菌生物膜的分散，并为慢性烧伤伤口感染造成潜在强效的抗生物膜处理策略
6. Treatment of Staphylococcus aureus Biofilm Infection by the Quorum-Sensing Inhibitor RIP [O] . Naomi Balaban, Oscar Cirioni, Andrea Giacometti, 2007

机译：群体感应抑制剂RIP治疗金黄色葡萄球菌生物膜感染
7. Treatment of Staphylococcus aureus Biofilm Infection by the Quorum-Sensing Inhibitor RIP▿ [O] . Balaban, Naomi, Cirioni, Oscar, Giacometti, Andrea, 2007

机译：群体感应抑制剂RIP▿治疗金黄色葡萄球菌生物膜感染

Treatment of Staphylococcus aureus biofilm infection by the quorum-sensing inhibitor RIP.

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