New Automated Method for Determining Postantifungal Effect of Amphotericin B against Candida Species: Effects of Concentration, Exposure Time, and Area under the Curve.

Chryssanthou E; Cars O; Sjolin J

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New Automated Method for Determining Postantifungal Effect of Amphotericin B against Candida Species: Effects of Concentration, Exposure Time, and Area under the Curve.

机译：确定两性霉素B对念珠菌物种的抑菌后作用的自动化新方法：浓度，暴露时间和曲线下面积的影响。

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The postantifungal effect (PAFE) of amphotericin B was determined with a BacT/Alert automated system, which is based on the colorimetric detection of CO(2). The levels of accuracy and precision of the automated method were high. Longer PAFEs were obtained for Candida albicans (P < 0.001), C. glabrata (P < 0.01), and C. krusei (P < 0.01) at increasing amphotericin B concentrations and exposure times.

机译：用BacT / Alert自动系统确定两性霉素B的抑菌后效果（PAFE），该系统基于比色法检测CO（2）。自动化方法的准确性和精密度很高。在增加两性霉素B浓度和暴露时间的情况下，白色念珠菌（P <0.001），光滑念珠菌（P <0.01）和克鲁氏梭菌（P <0.01）获得了更长的PAFE。

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《Antimicrobial agents and chemotherapy. 》 |2002年第12期| 共3页
作者
Chryssanthou E; Cars O; Sjolin J;
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正文语种 eng
中图分类治疗学 ;
关键词
Amphotericin B; Accident due to exposure to weather conditions; Carbon ion; 两性霉素B;

机译：Amphotericin B;Accident due to exposure to weather conditions;Carbon ion;两性霉素B;

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1. New Automated Method for Determining Postantifungal Effect of Amphotericin B against Candida Species: Effects of Concentration, Exposure Time, and Area under the Curve. [J] . Chryssanthou E, Cars O, Sjolin J Antimicrobial agents and chemotherapy. . 2002 ,第12期

机译：确定两性霉素B对念珠菌物种的抑菌后作用的自动化新方法：浓度，暴露时间和曲线下面积的影响。
2. Influence of temperature and concentration on the postantifungal effect and the effects of sub-MIC concentrations of four antifungal agents on previously treated Candida species. [J] . Garcia MT, Llorente MT, Minguez F, Chemotherapy: International Journal of Experimental and Clinical Chemotherapy . 2000 ,第4期

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6. New Automated Method for Determining Postantifungal Effect of Amphotericin B against Candida Species: Effects of Concentration Exposure Time and Area under the Curve [O] . Erja Chryssanthou, Otto Cars, Jan Sjölin 2002

机译：确定两性霉素B对念珠菌物种的抑菌后作用的自动化新方法：浓度暴露时间和曲线下面积的影响

7. New Automated Method for Determining Postantifungal Effect of Amphotericin B against Candida Species: Effects of Concentration, Exposure Time, and Area under the Curve [O] . Chryssanthou, Erja, Cars, Otto, Sjölin, Jan 2002

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New Automated Method for Determining Postantifungal Effect of Amphotericin B against Candida Species: Effects of Concentration, Exposure Time, and Area under the Curve.

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