Progression of coronary artery calcification: not down-and-out.

摘要

In the December 14, 2009, issue, McCullough et al presented a systematic review of randomized trials that used coronary artery calcification (CAC) progression as the primary end point. Despite the nonin-clusion of 2 eligible randomized placebo-controlled trials, we agree with their assertion that CAC progression has not been consistently reduced in any therapeutic randomized trial to date.