Current status of MRI in patients with inflammatory bowel disease colitis

摘要

Inflammatory bowel disease (IBD) is characterized by an inappropriate and ongoing activation of the bowel mucosal immune system in the presence of a normal bacterial flora.1 The current general view is that IBD manifests itself under certain environmental conditions on a genetic basis.2 The etiology and pathophysiology of IBD consist of 4 interacting factors: genetic, environmental, microbial, and immune.1'34 It includes 2 distinct diseases: ulcerative colitis (UC) and Crohn's disease (CD).1 In 10% of patients with IBD that is limited to the colon, it is initially not possible to distinguish UC from CD; this is the so-called indeterminate colitis (IC).1