Production of Ho-166 through Dy-164(n,gamma) Dy-165(n, gamma)(166) Dy(beta(-))(166) Ho and separation of Ho-166

摘要

After irradiation with thermal neutrons Dy-164 produces Ho-166 through the nuclear reaction: Dy-164(n,gamma) Dy-165(n,gamma) Dy-166 -->(beta-) Ho-166. Ho-166 has been separated from the bulk dysprosium target with the help of HPLC using Aminex A7 ion exchanger resin and alpha-hydroxyisobutyric acid (alpha-HIBA) as the mobile phase. The separation was quantitative and without any contamination from the dysprosium target. Method has also been developed to produce holmium free of alpha-HIBA ligands. Attempts have been made to produce no-carrier-added recoiled Ho-166 and Dy-165 in water. (C) 2004 Elsevier Ltd. All rights reserved.