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A water target with beam sweep for routine fluorine-18 production.

机译:带束扫的水靶,用于常规氟18生产。

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摘要

Fluorine-18 (18F) production with 18O-enriched water targets is well established world-wide. Heat transfer is still a critical point, however, when high beam currents are used to increase the amount of radioactivity per batch within an adequate irradiation period. The technique of beam sweep formerly used in Hannover for all targets has been adapted for this water target again. A titanium target with a beam sweep of up to 3 cm in the horizontal plane was designed to keep the total amount of enriched water low (2.06 ml), to allow beam currents of 30 microA for 1 h on a daily schedule and thereby to extend maintenance periods to more than 6 months. The design had to take into account that the target must be mounted on a target ladder with five additional positions and that the beam is carried by a 5.50 m beam line from a variable energy, multi-particle cyclotron (mc35, Scanditronix) to the target. The target has been in use for more than 130 consecutive runs with beam currents of about 30 microA at a target pressure of up to 15 bar without any maintenance. The mean value of the recovered radioactivity has reached 91.9+/-7.7% of the theoretically expected value at the end of bombardment (EOB).
机译:富含18O的水靶标的Fluor-18(18F)生产在世界范围内已得到公认。但是,当使用高束流在适当的照射时间内增加每批的放射性量时,传热仍然是关键点。汉诺威以前在所有目标上使用的束扫技术再次适用于该水目标。设计了一个钛靶,其在水平面内的射束扫描范围可达3厘米,以使浓缩水总量保持较低(2.06毫升),以允许每天30毫安的射束电流持续1 h,从而扩展保养期限要超过6个月。设计必须考虑到必须将靶标安装在具有五个其他位置的靶标阶梯上,并且束线应由5.50 m的束线从可变能量多粒子回旋加速器(mc35,Scanditronix)传输到靶标。该靶已在超过15 bar的目标压力下以约30 microA的束电流用于130多次连续运行而无需任何维护。轰击结束(EOB)时,回收的放射性平均值达到理论预期值的91.9 +/- 7.7%。

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