首页> 外文期刊>Applied radiation and isotopes: including data, instrumentation and methods for use in agriculture, industry and medicine >A simplified analytical approach to estimate the parameters required for strength determination of HDR 192Ir brachytherapy sources using a Farmer-type ionization chamber.
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A simplified analytical approach to estimate the parameters required for strength determination of HDR 192Ir brachytherapy sources using a Farmer-type ionization chamber.

机译:一种简化的分析方法,用于估计使用Farmer型电离室确定HDR 192Ir近距离放射治疗源的强度所需的参数。

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摘要

Measuring the strength of high dose rate (HDR) (192)Ir brachytherapy sources on receipt from the vendor is an important component of a quality assurance program. Owing to their ready availability in radiotherapy departments, the Farmer-type ionization chambers are also used to determine the strength of HDR (192)Ir brachytherapy sources. The use of a Farmer-type ionization chamber requires the estimation of the scatter correction factor along with positioning error (c) and the constant of proportionality (f) to determine the strength of HDR (192)Ir brachytherapy sources. A simplified approach based on a least squares method was developed for estimating the values of f and M(s). The seven distance method was followed to record the ionization chamber readings for parameterization of f and M(s). Analytically calculated values of M(s) were used to determine the room scatter correction factor (K(sc)). The Monte Carlo simulations were also carried out to calculate f and K(sc) to verify the magnitude of the parameters determined by the proposed analytical approach. The value of f determined using the simplified analytical approach was found to be in excellent agreement with the Monte Carlo simulated value (within 0.7%). Analytically derived values of K(sc) were also found to be in good agreement with the Monte Carlo calculated values (within 1.47%). Being far simpler than the presently available methods of evaluating f, the proposed analytical approach can be adopted for routine use by clinical medical physicists to estimate f by hand calculations.
机译:在从供应商处收到后测量高剂量率(HDR)(192)Ir近距离放射治疗源的强度是质量保证计划的重要组成部分。由于可以在放射治疗部门使用,Farmer型电离室也可用于确定HDR(192)Ir近距离放射治疗源的强度。使用Farmer型电离室需要估算散射校正因子以及定位误差(c)和比例常数(f),以确定HDR(192)Ir近距离放射治疗源的强度。开发了一种基于最小二乘法的简化方法来估计f和M(s)的值。遵循七距离法记录电离室读数,以参数化f和M(s)。 M(s)的解析计算值用于确定房间散射校正因子(K(sc))。还进行了蒙特卡洛模拟以计算f和K(sc),以验证所提出的分析方法确定的参数的大小。发现使用简化分析方法确定的f值与蒙特卡洛模拟值(0.7%以内)非常吻合。还发现,分析得出的K(sc)值与Monte Carlo计算值(在1.47%之内)非常吻合。与目前可用的评估f的方法相比,该方法要简单得多,所建议的分析方法可被临床医学物理学家日常使用以通过手工计算来估计f。

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