Side-Stream Simulated Moving-Bed Chromatography for Multicomponent Separation

摘要

Simulated countercurrent moving-bed chromatography is a thermal separation process which, due to its high selectivity, is often used to separate very similar molecules. As with a rectification column, a conventional chromatographic separator unit is designed with two product outlets for each component mixtures are more likely to be encountered in reality, the current work extends distillation's use of side-stream withdrawal to moving-bed chromatographyin order to investigate the suitability of a side-stream SMB (simulated countercurrent moving-bed spearator) for separating multi-component systems. In addition, generally applicable rules about the behavior and separation performance of the unit will also be derived.