Degree of immune suppression and risk of HIV-related Hodgkin lymphoma: time points matter.

摘要

We thank Dolcetti and colleagues for their interest in our report and for highlighting our observation of lymphocytopenia close in time to diagnosis of HIV-related Hodgkin lymphoma (HL). We agree that this finding makes the timing of CD4+ assessment critical to elucidating the relationship between degree of immune suppression and HL risk in HIV-infected cohorts and that it complicates comparisons between our findings and those based upon CD4+ counts in the year preceding HL diagnosis