Microvascular sequestration of Plasmodium falciparum.

摘要

A 2-year-old boy presented to a clinic in rural Mali with fever and malaise. Thick and thin blood films stained with Giemsa (left and right, respectively) revealed that 25.7% of circulating erythrocytes were parasitized with Plasmodium falciparum (273 450 ring-stage parasites per microliter of whole blood). The child had an axillary temperature of 36.9癈 and a hemoglobin level of 78 g/L. Eight hours after the first blood smear, a second thin blood film showed 0.6% parasitemia. The child was treated with oral artesunate and amodiaquine over 3 days. Cure was documented on the fourth day by a negative blood smear.