Aspirin Is Associated with Decreased Allogeneic Transfusions and Resource Utilization following Hip Fracture Care

摘要

The purpose of our study is to assess the relationship and compare the impact of aspirin, enoxaparin, and warfarin use on postoperative anemia, allogenic transfusions, and resource utilization following hip fracture fixation. This is a retrospective study at a Level 1 trauma center with 450 geriatric hip fracture patients who underwent hip fracture surgery and chemoprophylaxis. Hip fracture patients were separated into three cohorts depending on the type of chemoprophylaxis administered aspirin, enoxaparin, or warfarin. Initially, all three cohorts were assessed for baseline characteristics, postoperative anemia, transfusion rates, and resource utilization. Next, aspirin and enoxaparin were comparatively evaluated for the same variables. Four hundred and fifty patients met inclusion criteria for the first portion of this study. No baseline variance was evident among the three cohorts except for body mass index (p?=?0.007) and diagnosis of congestive heart failure (p?=?0.001). Outcomes were insignificant for in-hospital mortality (p?=?0.19), postoperative anemia (p?=?0.43), hemoglobin levels (p?=?0.91), and ?hemoglobin (p?=?0.99), length-of-stay (p?=?0.12), disposition (p?=?0.13), and 30-day readmission (p =0.09). The transfusion rate (p?