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首页> 外文期刊>Blood: The Journal of the American Society of Hematology >Innovation in myeloma treatments PARP excellence!
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Innovation in myeloma treatments PARP excellence!

机译:骨髓瘤治疗方面的创新使PARP卓越!

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摘要

Over the past decade we have seen new treatments available for patients; including proteasome inhibitors and the so-called immunomodulatory drugs. Combination strategies, often in conjunction with autolo-gous stem cell transplantation, have maximized clinical efficacy of these drugs and some patients now enjoy durable remissions, including a minor subset that is cured from the disease. However, most patients relapse, some with high-risk genetic features relapse after only a short period of disease control. Improved strategies are needed.
机译:在过去的十年中,我们看到了可用于患者的新疗法。包括蛋白酶体抑制剂和所谓的免疫调节药物。通常与自体干细胞移植相结合的联合策略已使这些药物的临床疗效最大化,一些患者现在享有持久的缓解,包括从疾病中治愈的一小部分。但是,大多数患者会复发,某些具有高风险遗传特征的患者仅在短期控制疾病后即可复发。需要改进的策略。

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