HER2 Gene Amplification by Fluorescence In Situ Hybridization (FISH) Compared With Immunohistochemistry (IHC) in 122 Equivocal Gastric Cancer Cases

Xiaoyan Liu; Xiaoling Wang; Bo Wang; Guoping Ren; Wei Ding

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HER2 Gene Amplification by Fluorescence In Situ Hybridization (FISH) Compared With Immunohistochemistry (IHC) in 122 Equivocal Gastric Cancer Cases

机译：荧光原位杂交（FISH）和免疫组织化学（IHC）对HER2基因扩增在122例胃癌中的比较

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To determine the frequency of HER2eu amplification and the relationship between HER2eu expression and clinicopathologic features in gastric cancers scored immunohistochemistry (IHC) 2 +. Methods: A total of 122 gastric cancer cases scored IHC 2 + were retrospectively analyzed for HER2 amplification by fluorescence in situ hybridization (FISH). The correlation between HER2eu expression and clinicopathologic features was analyzed.

机译：为了确定胃癌中HER2 / neu扩增的频率以及HER2 / neu表达与临床病理特征之间的关系，采用免疫组织化学（IHC）2 +评分。方法：采用荧光原位杂交技术（FISH）回顾性分析了122例IHC 2 +评分为高的胃癌患者的HER2扩增。分析了HER2 / neu表达与临床病理特征之间的相关性。

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《Applied immunohistochemistry and molecular morphology: AIMM》 |2016年第7期|共6页
作者
Xiaoyan Liu; Xiaoling Wang; Bo Wang; Guoping Ren; Wei Ding;
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正文语种 eng
中图分类人体形态学;
关键词
gastric cancer; fluorescence in situ hybridization; HER2eu;

机译：胃癌;荧光原位杂交;HER2 / neu;

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专利

1. HER2 Gene Amplification by Fluorescence In Situ Hybridization (FISH) Compared With Immunohistochemistry (IHC) in 122 Equivocal Gastric Cancer Cases [J] . Xiaoyan Liu, Xiaoling Wang, Bo Wang, Applied immunohistochemistry and molecular morphology: AIMM . 2016,第7期

机译：荧光原位杂交（FISH）和免疫组织化学（IHC）对HER2基因扩增在122例胃癌中的比较
2. Chromogenic in situ hybridization (CISH) to detect HER2 gene amplification in breast and gastric cancer: Comparison with immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH) [J] . KiyoseS., IgarashiH., NaguraK., Pathology International . 2012,第11期

机译：显色原位杂交（CISH）检测乳腺癌和胃癌中HER2基因的扩增：与免疫组织化学（IHC）和荧光原位杂交（FISH）的比较
3. HER-2 gene amplification by fluorescence in situ hybridization (FISH) compared with immunohistochemistry (IHC) in breast cancer: a study of 528 equivocal cases. [J] . Han Zhang, Guoping Ren, Xiaoling Wang, Breast cancer research and treatment. . 2012,第2期

机译：荧光原位杂交（FISH）与免疫组化（IHC）技术比较乳腺癌中的HER-2基因：528例疑似病例的研究。
4. A nCounter CNV Assay to Detect HER2 Amplification: A Correlation Study with Immunohistochemistry and Fluorescence In Situ Hybridization in a Cohort of 220 Advanced Gastric Cancer Tissues [C] . Kyoung-Mee Kim, Soomin Ahn, Mineui Hong, International Molecular Medicine Tri-Conference. . 2016

机译：NCounter CNV测定检测HER2扩增：在220个晚期胃癌组织队列中的免疫组织化学和荧光的相关性研究
5. Deletions of tumor suppressor genes in human lung cancers: A fluorescence in situ hybridization (FISH) study [D] . Liu, Jun. 1998

机译：人类肺癌中肿瘤抑制基因的缺失：荧光原位杂交（FISH）研究
6. Concomitant Detection of HER2 Protein and Gene Alterations by Immunohistochemistry (IHC) and Silver Enhanced In Situ Hybridization (SISH) Identifies HER2 Positive Breast Cancer with and without Gene Amplification [O] . Zsuzsanna Varga, Raymond R. Tubbs, Holger Moch -1

机译：免疫组织化学（IHC）和银增强原位杂交（SISH）同时检测HER2蛋白和基因改变可鉴定有无基因扩增的HER2阳性乳腺癌
7. Concomitant Detection of HER2 Protein and Gene Alterations by Immunohistochemistry (IHC) and Silver Enhanced In Situ Hybridization (SISH) Identifies HER2 Positive Breast Cancer with and without Gene Amplification [O] . Varga, Zsuzsanna, Tubbs, Raymond R, Moch, Holger 2014

机译：免疫组织化学（IHC）和银增强原位杂交（SISH）同时检测HER2蛋白和基因改变可鉴定有无基因扩增的HER2阳性乳腺癌
8. Fluorescence In Situ Hybridization(FISH) or Other In Situ Hybridization(ISH) Testing of Uterine Cervical Cells to Predict Precancer and Cancer. (Final). [R] . Uhlig, K., Earley, A., Lamont, J., 2013

机译：子宫颈细胞的荧光原位杂交（FIsH）或其他原位杂交（IsH）测试预测癌前病变和癌症。（最后）。

HER2 Gene Amplification by Fluorescence In Situ Hybridization (FISH) Compared With Immunohistochemistry (IHC) in 122 Equivocal Gastric Cancer Cases

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