A new role for P(k): finding the 1 in a million.

摘要

It is said that there are more than 400 blood group antigens on the red blood cell and of these, about 40 have known clinical significance. Significance in this context refers to transfusion-related concerns, typically meaning the ability of an antibody, when in proximity to the cognate antigen, to cause hemolysis-intravascularly, extravascularly or in utero (as in transfusion reactions or hemolytic disease of the newborn).