Researchers from Sichuan University Detail Findings in Cancer (Development and Validation of Nomograms for Predicting Survival and Recurrence In Patients With Parotid Gland Cancer)

摘要

2021 SEP 17 (NewsRx) - By a News Reporter-Staff News Editor at Disease Prevention Daily - New research on Cancer is the subject of a report. According to news reporting originating from Chengdu, People's Republic of China, by NewsRx correspondents, research stated, "To develop nomograms for predicting recurrence risk and long-term survival in patients with parotid gland cancer (PGC). A total of 301 consecutive patients with PGC who underwent surgery were enrolled and randomly divided into a training cohort (n=210) and a validation cohort (n=91)." Financial support for this research came from National Natural Science Foundation of China (NSFC). Our news editors obtained a quote from the research from Sichuan University, "Predictive nomograms were constructed based on the independent indicators of overall survival (OS) and disease-free survival (DFS) as determined by multivariate Cox regression analysis. The discrimination and calibration of nomograms were evaluated using C-indices and calibration curves. Six independent predictors of OS were identified. Incorporating these factors, the nomogram showed good concordance statistics of 0.84 and 0.78 in predicting the 5-year OS in the training and validation cohorts. Five independent predictors of DFS were identified and integrated into the nomogram. The concordance statistics were 0.84 and 0.74 in predicting the 5-year DFS in the training and validation cohorts.