Instituto Fernandes Figueira Researchers Further Understanding of Zika Virus (Time to Evaluate the Clinical Repercussions of Zika Virus Vertical Transmission? A Systematic Review)

摘要

2021 SEP 17 (NewsRx) - By a News Reporter-Staff News Editor at Disease Prevention Daily - Research findings on Zika virus are discussed in a new report. According to news originating from Rio de Janeiro, Brazil, by NewsRx editors, the research stated, "Vertical transmission of Zika Virus (ZIKV) can be associated with several clinical features in newborn infants." Funders for this research include Fundacao de Amparo a Pesquisa do Estado do Rio Grande do Sul; Fundacao Oswaldo Cruz. Our news journalists obtained a quote from the research from Instituto Fernandes Figueira: "The goal of the present review was to analyze the current state of knowledge regarding clinical repercussions following perinatal exposure to ZIKV in children up to 3 years of age. A systematic review of published studies was carried out, without the restriction of language or date of publication, identified in the databases PubMed, Virtual Health Library (BVS), Scopus, and Web of Science and the catalog for CAPES theses and dissertations. According to the proposed flowchart, the bibliographic search resulted in 1,563 papers. Of these, according to the eligibility criteria, 70 were selected for systematic review; all were published between 2016 and 2021. Regarding clinical findings, 19 papers evaluated clinical imaging alterations, 21 ophthalmic manifestations, and 39 evaluated the central nervous system; of these, 15 analyzed neuro-psychomotor development. The remainder evaluated audiological (n = 14), nutritional (n = 14), orthopedic (n = 7), cardiorespiratory (n = 5), genitourinary (n = 3) or endocrinological (n = 1) manifestations."