Investigators at University of Minnesota Report Findings in Throm-bocytopenia (Preoperative Platelet Transfusions: a Retrospective Review of Pediatric Patients With Thrombocytopenia, 2011-2016)

摘要

2021 SEP 17(NewsRx)-Bya News Reporter-Staff News Editor at Disease Prevention Daily-Investigators publish new report on Hematologic Diseases and Conditions - Thrombocytopenia. According to news originating from Minneapolis, Minnesota, by NewsRx correspondents, research stated, "Thrombocytopenia is a common perioperative clinical problem and preoperative platelet transfusion prior to surgery is standard practice. Recent platelet trials and literature reviews have found no association between platelet count and bleeding incidence except when platelet count is extremely low." Our news journalists obtained a quote from the research from the University of Minnesota, "Our aim was to evaluate the bleeding risk and the overall platelet transfusion management among pediatric patients with severe thrombocytopenia based on whether they were preoperatively transfused versus transfused at time of incision. This is a retrospective analysis of pediatric patients with a platelet count <= 50 x 10(9)/L in the 12 h prior to surgery at a single tertiary pediatric hospital from 2011 to 2016. Eligible patients were <= 21 years old. Patients with necrotizing enterocolitis and neonates were excluded. The primary outcome was postoperative bleeding complications. Additional outcomes were preoperative platelet change and weight adjusted transfusion volumes. A total of 37 patients were included in this analysis of which 29 (78%) received preoperative platelet transfusions within 12 h prior to surgery. No postoperative bleeding complications occurred 30 days after operation, regardless of preoperative transfusion status.